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QBiC-Pred: quantitative predictions of transcription factor binding changes due to sequence variants
Non-coding genetic variants/mutations can play functional roles in the cell by disrupting regulatory interactions between transcription factors (TFs) and their genomic target sites. For most human TFs, a myriad of DNA-binding models are available and could be used to predict the effects of DNA mutat...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602471/ https://www.ncbi.nlm.nih.gov/pubmed/31114870 http://dx.doi.org/10.1093/nar/gkz363 |