Cargando…
DNAvisualization.org: a serverless web tool for DNA sequence visualization
Raw DNA sequences contain an immense amount of meaningful biological information. However, these sequences are hard for humans to intuitively interpret. To solve this problem, a number of methods have been proposed to transform DNA sequences into two-dimensional visualizations. DNAvisualization.org...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602497/ https://www.ncbi.nlm.nih.gov/pubmed/31170285 http://dx.doi.org/10.1093/nar/gkz404 |
_version_ | 1783431389528457216 |
---|---|
author | Lee, Benjamin D Timony, Michael A Ruiz, Pablo |
author_facet | Lee, Benjamin D Timony, Michael A Ruiz, Pablo |
author_sort | Lee, Benjamin D |
collection | PubMed |
description | Raw DNA sequences contain an immense amount of meaningful biological information. However, these sequences are hard for humans to intuitively interpret. To solve this problem, a number of methods have been proposed to transform DNA sequences into two-dimensional visualizations. DNAvisualization.org implements several of these methods in a cost effective and performant manner via a novel, entirely serverless architecture. By taking advantage of recent developments in serverless parallel computing and selective data retrieval, the website is able to offer users the ability to visualize up to thirty 4.5 Mb DNA sequences simultaneously using one of five supported methods and to export these visualizations in a variety of publication-ready formats. |
format | Online Article Text |
id | pubmed-6602497 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-66024972019-07-05 DNAvisualization.org: a serverless web tool for DNA sequence visualization Lee, Benjamin D Timony, Michael A Ruiz, Pablo Nucleic Acids Res Web Server Issue Raw DNA sequences contain an immense amount of meaningful biological information. However, these sequences are hard for humans to intuitively interpret. To solve this problem, a number of methods have been proposed to transform DNA sequences into two-dimensional visualizations. DNAvisualization.org implements several of these methods in a cost effective and performant manner via a novel, entirely serverless architecture. By taking advantage of recent developments in serverless parallel computing and selective data retrieval, the website is able to offer users the ability to visualize up to thirty 4.5 Mb DNA sequences simultaneously using one of five supported methods and to export these visualizations in a variety of publication-ready formats. Oxford University Press 2019-07-02 2019-06-06 /pmc/articles/PMC6602497/ /pubmed/31170285 http://dx.doi.org/10.1093/nar/gkz404 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Web Server Issue Lee, Benjamin D Timony, Michael A Ruiz, Pablo DNAvisualization.org: a serverless web tool for DNA sequence visualization |
title | DNAvisualization.org: a serverless web tool for DNA sequence visualization |
title_full | DNAvisualization.org: a serverless web tool for DNA sequence visualization |
title_fullStr | DNAvisualization.org: a serverless web tool for DNA sequence visualization |
title_full_unstemmed | DNAvisualization.org: a serverless web tool for DNA sequence visualization |
title_short | DNAvisualization.org: a serverless web tool for DNA sequence visualization |
title_sort | dnavisualization.org: a serverless web tool for dna sequence visualization |
topic | Web Server Issue |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602497/ https://www.ncbi.nlm.nih.gov/pubmed/31170285 http://dx.doi.org/10.1093/nar/gkz404 |
work_keys_str_mv | AT leebenjamind dnavisualizationorgaserverlesswebtoolfordnasequencevisualization AT timonymichaela dnavisualizationorgaserverlesswebtoolfordnasequencevisualization AT ruizpablo dnavisualizationorgaserverlesswebtoolfordnasequencevisualization |