Cargando…

DNAvisualization.org: a serverless web tool for DNA sequence visualization

Raw DNA sequences contain an immense amount of meaningful biological information. However, these sequences are hard for humans to intuitively interpret. To solve this problem, a number of methods have been proposed to transform DNA sequences into two-dimensional visualizations. DNAvisualization.org...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Benjamin D, Timony, Michael A, Ruiz, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602497/
https://www.ncbi.nlm.nih.gov/pubmed/31170285
http://dx.doi.org/10.1093/nar/gkz404
_version_ 1783431389528457216
author Lee, Benjamin D
Timony, Michael A
Ruiz, Pablo
author_facet Lee, Benjamin D
Timony, Michael A
Ruiz, Pablo
author_sort Lee, Benjamin D
collection PubMed
description Raw DNA sequences contain an immense amount of meaningful biological information. However, these sequences are hard for humans to intuitively interpret. To solve this problem, a number of methods have been proposed to transform DNA sequences into two-dimensional visualizations. DNAvisualization.org implements several of these methods in a cost effective and performant manner via a novel, entirely serverless architecture. By taking advantage of recent developments in serverless parallel computing and selective data retrieval, the website is able to offer users the ability to visualize up to thirty 4.5 Mb DNA sequences simultaneously using one of five supported methods and to export these visualizations in a variety of publication-ready formats.
format Online
Article
Text
id pubmed-6602497
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-66024972019-07-05 DNAvisualization.org: a serverless web tool for DNA sequence visualization Lee, Benjamin D Timony, Michael A Ruiz, Pablo Nucleic Acids Res Web Server Issue Raw DNA sequences contain an immense amount of meaningful biological information. However, these sequences are hard for humans to intuitively interpret. To solve this problem, a number of methods have been proposed to transform DNA sequences into two-dimensional visualizations. DNAvisualization.org implements several of these methods in a cost effective and performant manner via a novel, entirely serverless architecture. By taking advantage of recent developments in serverless parallel computing and selective data retrieval, the website is able to offer users the ability to visualize up to thirty 4.5 Mb DNA sequences simultaneously using one of five supported methods and to export these visualizations in a variety of publication-ready formats. Oxford University Press 2019-07-02 2019-06-06 /pmc/articles/PMC6602497/ /pubmed/31170285 http://dx.doi.org/10.1093/nar/gkz404 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Web Server Issue
Lee, Benjamin D
Timony, Michael A
Ruiz, Pablo
DNAvisualization.org: a serverless web tool for DNA sequence visualization
title DNAvisualization.org: a serverless web tool for DNA sequence visualization
title_full DNAvisualization.org: a serverless web tool for DNA sequence visualization
title_fullStr DNAvisualization.org: a serverless web tool for DNA sequence visualization
title_full_unstemmed DNAvisualization.org: a serverless web tool for DNA sequence visualization
title_short DNAvisualization.org: a serverless web tool for DNA sequence visualization
title_sort dnavisualization.org: a serverless web tool for dna sequence visualization
topic Web Server Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602497/
https://www.ncbi.nlm.nih.gov/pubmed/31170285
http://dx.doi.org/10.1093/nar/gkz404
work_keys_str_mv AT leebenjamind dnavisualizationorgaserverlesswebtoolfordnasequencevisualization
AT timonymichaela dnavisualizationorgaserverlesswebtoolfordnasequencevisualization
AT ruizpablo dnavisualizationorgaserverlesswebtoolfordnasequencevisualization