Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies

The Plasmodium falciparum reticulocyte-binding protein homolog 5 (PfRH5) is the leading target for next-generation vaccines against the disease-causing blood-stage of malaria. However, little is known about how human antibodies confer functional immunity against this antigen. We isolated a panel of...

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Detalles Bibliográficos
Autores principales: Alanine, Daniel G.W., Quinkert, Doris, Kumarasingha, Rasika, Mehmood, Shahid, Donnellan, Francesca R., Minkah, Nana K., Dadonaite, Bernadeta, Diouf, Ababacar, Galaway, Francis, Silk, Sarah E., Jamwal, Abhishek, Marshall, Jennifer M., Miura, Kazutoyo, Foquet, Lander, Elias, Sean C., Labbé, Geneviève M., Douglas, Alexander D., Jin, Jing, Payne, Ruth O., Illingworth, Joseph J., Pattinson, David J., Pulido, David, Williams, Barnabas G., de Jongh, Willem A., Wright, Gavin J., Kappe, Stefan H.I., Robinson, Carol V., Long, Carole A., Crabb, Brendan S., Gilson, Paul R., Higgins, Matthew K., Draper, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602525/
https://www.ncbi.nlm.nih.gov/pubmed/31204103
http://dx.doi.org/10.1016/j.cell.2019.05.025

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