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An integrated experimental-computational approach for predicting virulence in New Zealand white rabbits and humans following inhalation exposure to Bacillus anthracis spores

Inhalation of Bacillus anthracis spores can lead to an anthrax infection that can be fatal. Previously published mathematical models have extrapolated kinetic rates associated with bacterial growth in New Zealand White (NZW) rabbits to humans, but to date, actual measurements of the underlying proce...

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Detalles Bibliográficos
Autores principales: Hess, Becky M., Thomas, Dennis G., Weber, Thomas J., Hutchison, Janine R., Straub, Timothy M., Bruckner-Lea, Cynthia J., Powell, Joshua D., Kabilan, Senthil, Corley, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602573/
https://www.ncbi.nlm.nih.gov/pubmed/31260462
http://dx.doi.org/10.1371/journal.pone.0219160