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Seroprevalence of Coxiella burnetii (Q fever) Exposure in Humans on Reunion Island

After the documentation of sporadic cases of Q fever endocarditis, we conducted a serosurvey to assess Coxiella burnetii exposure on Reunion Island. Two hundred forty-one stored frozen human sera were analyzed using an immunofluorescence assay. The weighted seroprevalence of Q fever was of 6.81% (95...

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Autores principales: Jaubert, Julien, Naze, Florence, Camuset, Guillaume, Larrieu, Sophie, Pascalis, Hervé, Guernier, Vanina, Naty, Nadège, Bertolotti, Antoine, Manaquin, Rodolphe, Mboussou, Yoan, Atiana, Laura, Picot, Sandrine, Filleul, Laurent, Tortosa, Pablo, Cardinale, Eric, Gérardin, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602885/
https://www.ncbi.nlm.nih.gov/pubmed/31281854
http://dx.doi.org/10.1093/ofid/ofz227
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author Jaubert, Julien
Naze, Florence
Camuset, Guillaume
Larrieu, Sophie
Pascalis, Hervé
Guernier, Vanina
Naty, Nadège
Bertolotti, Antoine
Manaquin, Rodolphe
Mboussou, Yoan
Atiana, Laura
Picot, Sandrine
Filleul, Laurent
Tortosa, Pablo
Cardinale, Eric
Gérardin, Patrick
author_facet Jaubert, Julien
Naze, Florence
Camuset, Guillaume
Larrieu, Sophie
Pascalis, Hervé
Guernier, Vanina
Naty, Nadège
Bertolotti, Antoine
Manaquin, Rodolphe
Mboussou, Yoan
Atiana, Laura
Picot, Sandrine
Filleul, Laurent
Tortosa, Pablo
Cardinale, Eric
Gérardin, Patrick
author_sort Jaubert, Julien
collection PubMed
description After the documentation of sporadic cases of Q fever endocarditis, we conducted a serosurvey to assess Coxiella burnetii exposure on Reunion Island. Two hundred forty-one stored frozen human sera were analyzed using an immunofluorescence assay. The weighted seroprevalence of Q fever was of 6.81% (95% confidence interval, 4.02%–9.59%). Despite the absence of infection in youths <20 years of age, exposure was not driven by age or by gender. There was a spatial disparity in exposure across the island, with higher prevalence being reported in regions where ruminant farms are present. The seroprevalence pattern suggests that Q fever is endemic on Reunion Island.
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spelling pubmed-66028852019-07-05 Seroprevalence of Coxiella burnetii (Q fever) Exposure in Humans on Reunion Island Jaubert, Julien Naze, Florence Camuset, Guillaume Larrieu, Sophie Pascalis, Hervé Guernier, Vanina Naty, Nadège Bertolotti, Antoine Manaquin, Rodolphe Mboussou, Yoan Atiana, Laura Picot, Sandrine Filleul, Laurent Tortosa, Pablo Cardinale, Eric Gérardin, Patrick Open Forum Infect Dis Brief Report After the documentation of sporadic cases of Q fever endocarditis, we conducted a serosurvey to assess Coxiella burnetii exposure on Reunion Island. Two hundred forty-one stored frozen human sera were analyzed using an immunofluorescence assay. The weighted seroprevalence of Q fever was of 6.81% (95% confidence interval, 4.02%–9.59%). Despite the absence of infection in youths <20 years of age, exposure was not driven by age or by gender. There was a spatial disparity in exposure across the island, with higher prevalence being reported in regions where ruminant farms are present. The seroprevalence pattern suggests that Q fever is endemic on Reunion Island. Oxford University Press 2019-05-15 /pmc/articles/PMC6602885/ /pubmed/31281854 http://dx.doi.org/10.1093/ofid/ofz227 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Jaubert, Julien
Naze, Florence
Camuset, Guillaume
Larrieu, Sophie
Pascalis, Hervé
Guernier, Vanina
Naty, Nadège
Bertolotti, Antoine
Manaquin, Rodolphe
Mboussou, Yoan
Atiana, Laura
Picot, Sandrine
Filleul, Laurent
Tortosa, Pablo
Cardinale, Eric
Gérardin, Patrick
Seroprevalence of Coxiella burnetii (Q fever) Exposure in Humans on Reunion Island
title Seroprevalence of Coxiella burnetii (Q fever) Exposure in Humans on Reunion Island
title_full Seroprevalence of Coxiella burnetii (Q fever) Exposure in Humans on Reunion Island
title_fullStr Seroprevalence of Coxiella burnetii (Q fever) Exposure in Humans on Reunion Island
title_full_unstemmed Seroprevalence of Coxiella burnetii (Q fever) Exposure in Humans on Reunion Island
title_short Seroprevalence of Coxiella burnetii (Q fever) Exposure in Humans on Reunion Island
title_sort seroprevalence of coxiella burnetii (q fever) exposure in humans on reunion island
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602885/
https://www.ncbi.nlm.nih.gov/pubmed/31281854
http://dx.doi.org/10.1093/ofid/ofz227
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