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PSD-95 deficiency disrupts PFC-associated function and behavior during neurodevelopment

Postsynaptic density protein-95 (PSD-95) is a major regulator in the maturation of excitatory synapses by interacting and trafficking N-methyl-D-aspartic acid receptors (NMDAR) and α-amino-3-hydroxy-5-methyl-4-isox-azoleproprionic acid receptors (AMPAR) to the postsynaptic membrane. PSD-95 disruptio...

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Detalles Bibliográficos
Autores principales: Coley, Austin A., Gao, Wen-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602948/
https://www.ncbi.nlm.nih.gov/pubmed/31263190
http://dx.doi.org/10.1038/s41598-019-45971-w