Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain

Exogenous metabolites from microbial and dietary origins have profound effects on host metabolism. Here, we report that a sub-population of lipid droplets (LDs), which are conserved organelles for fat storage, is defined by metabolite-modulated targeting of the C. elegans seipin ortholog, SEIP-1. Lo...

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Detalles Bibliográficos
Autores principales: Cao, Zhe, Hao, Yan, Fung, Chun Wing, Lee, Yiu Yiu, Wang, Pengfei, Li, Xuesong, Xie, Kang, Lam, Wen Jiun, Qiu, Yifei, Tang, Ben Zhong, Shui, Guanghou, Liu, Pingsheng, Qu, Jianan, Kang, Byung-Ho, Mak, Ho Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602954/
https://www.ncbi.nlm.nih.gov/pubmed/31263173
http://dx.doi.org/10.1038/s41467-019-10835-4

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