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Crizotinib in Chinese Patients with ROS1-Rearranged Advanced Non‒Small-Cell Lung Cancer in Routine Clinical Practice
BACKGROUND: Approximately 1–2% of patients with non‒small-cell lung cancer (NSCLC) harbor ROS1 rearrangements. Crizotinib, an oral small-molecule tyrosine kinase inhibitor (TKI) that targets anaplastic lymphoma kinase (ALK), MET, and ROS1, has shown marked antitumor activity in patients with ROS1-po...
Autores principales: | Liu, Chang, Yu, Hui, Chang, Jianhua, Chen, Haiquan, Li, Yuan, Zhao, Weixin, Zhao, Kuaile, Zhu, Zhengfei, Sun, Si, Fan, Min, Wang, Jialei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602983/ https://www.ncbi.nlm.nih.gov/pubmed/30976989 http://dx.doi.org/10.1007/s11523-019-00636-6 |
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