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Major changes in chromosomal somy, gene expression and gene dosage driven by Sb(III) in Leishmania braziliensis and Leishmania panamensis
Leishmania braziliensis and Leishmania panamensis are two species clinically and epidemiologically important, among others because of their relative resistance to first-line drugs (antimonials). The precise mechanism underlying the ability of these species to survive antimony treatment remains unkno...
Autores principales: | Patino, Luz H., Imamura, Hideo, Cruz-Saavedra, Lissa, Pavia, Paula, Muskus, Carlos, Méndez, Claudia, Dujardin, Jean Claude, Ramírez, Juan David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603004/ https://www.ncbi.nlm.nih.gov/pubmed/31263131 http://dx.doi.org/10.1038/s41598-019-45538-9 |
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