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Major changes in chromosomal somy, gene expression and gene dosage driven by Sb(III) in Leishmania braziliensis and Leishmania panamensis

Leishmania braziliensis and Leishmania panamensis are two species clinically and epidemiologically important, among others because of their relative resistance to first-line drugs (antimonials). The precise mechanism underlying the ability of these species to survive antimony treatment remains unkno...

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Detalles Bibliográficos
Autores principales: Patino, Luz H., Imamura, Hideo, Cruz-Saavedra, Lissa, Pavia, Paula, Muskus, Carlos, Méndez, Claudia, Dujardin, Jean Claude, Ramírez, Juan David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603004/
https://www.ncbi.nlm.nih.gov/pubmed/31263131
http://dx.doi.org/10.1038/s41598-019-45538-9

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