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A novel method for rapid detection of a Helicobacter pylori infection using a γ-glutamyltranspeptidase-activatable fluorescent probe

A γ-glutamyl hydroxymethyl rhodamine green probe (gGlu-HMRG) reacts with γ-glutamyltranspeptidase (GGT) and immediately produces fluorescence, is clinically applied for real-time cancers’ visualization. Since Helicobacter pylori produces GGT, this study aimed to investigate whether gGlu-HMRG can be...

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Detalles Bibliográficos
Autores principales: Akashi, Taro, Isomoto, Hajime, Matsushima, Kayoko, Kamiya, Mako, Kanda, Tsutomu, Nakano, Masayuki, Onoyama, Takumi, Fujii, Masashi, Akada, Junko, Akazawa, Yuko, Ohnita, Ken, Takeshima, Fuminao, Nakao, Kazuhiko, Urano, Yasuteru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603024/
https://www.ncbi.nlm.nih.gov/pubmed/31263136
http://dx.doi.org/10.1038/s41598-019-45768-x