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Individual Vulnerability to Stress Is Associated With Increased Demand for Intravenous Heroin Self-administration in Rats
Opioid use is a widespread epidemic, and traumatic stress exposure is a critical risk factor in opioid use and relapse. There is a significant gap in our understanding of how stress contributes to heroin use, and there are limited studies investigating individual differences underlying stress reacti...
Autores principales: | Stafford, Nathaniel P., Kazan, Theodore N., Donovan, Colleen M., Hart, Erin E., Drugan, Robert C., Charntikov, Sergios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603087/ https://www.ncbi.nlm.nih.gov/pubmed/31293400 http://dx.doi.org/10.3389/fnbeh.2019.00134 |
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