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A Canine Model of Hemorrhagic Transformation Using Recombinant Tissue Plasminogen Activator Administration After Acute Ischemic Stroke
Early reperfusion of occluded arteries via recombinant tissue plasminogen activator (rtPA) administration is considered to be an effective strategy for the treatment of acute ischemic stroke. However, delayed administration of rtPA may cause severe hemorrhagic transformation (HT) and undesirable neu...
Autores principales: | Jiang, Run-Hao, Zu, Qing-Quan, Xu, Xiao-Quan, Wang, Bin, Ding, Ye, Wang, Jun, Liu, Sheng, Shi, Hai-Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603151/ https://www.ncbi.nlm.nih.gov/pubmed/31293509 http://dx.doi.org/10.3389/fneur.2019.00673 |
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