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Endogenous Expression of the Human CD83 Attenuates EAE Symptoms in Humanized Transgenic Mice and Increases the Activity of Regulatory T Cells
The CD83 is a type I membrane protein and part of the immunoglobulin superfamily of receptors. CD83 is involved in the regulation of antigen presentation and dendritic cell dependent allogeneic T cell proliferation. A soluble form of CD83 inhibits dendritic cell maturation and function. Furthermore,...
Autores principales: | Zinser, Elisabeth, Naumann, Ronald, Wild, Andreas B., Michalski, Julia, Deinzer, Andrea, Stich, Lena, Kuhnt, Christine, Steinkasserer, Alexander, Knippertz, Ilka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603205/ https://www.ncbi.nlm.nih.gov/pubmed/31293592 http://dx.doi.org/10.3389/fimmu.2019.01442 |
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