Epoxy-Oxylipins and Soluble Epoxide Hydrolase Metabolic Pathway as Targets for NSAID-Induced Gastroenteropathy and Inflammation-Associated Carcinogenesis

Polyunsaturated fatty acids (PUFAs) including epoxide-modified ω-3 and ω-6 fatty acids are made via oxidation to create highly polarized carbon-oxygen bonds crucial to their function as signaling molecules. A critical PUFA, arachidonic acid (ARA), is metabolized to a diverse set of lipids signaling...

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Detalles Bibliográficos
Autores principales: Jones, Ryan D., Liao, Jie, Tong, Xin, Xu, Dandan, Sun, Leyu, Li, Haonan, Yang, Guang-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603234/
https://www.ncbi.nlm.nih.gov/pubmed/31293429
http://dx.doi.org/10.3389/fphar.2019.00731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603234/
https://www.ncbi.nlm.nih.gov/pubmed/31293429
http://dx.doi.org/10.3389/fphar.2019.00731

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