Cathelicidin- derived PR39 protects enterohemorrhagic Escherichia coli O157:H7 challenged mice by improving epithelial function and balancing the microbiota in the intestine

The zoonotic enterohaemorrhagic Escherichia coli (EHEC) O157:H7 can disrupt intestinal epithelial barrier function and in turn leading to serious intestinal and systemic disease. PR39 could effectively inhibit the growth of Gram-negative bacteria, but there is little knowledge of its effects on inte...

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Detalles Bibliográficos
Autores principales: Haiwen, Zhang, Rui, Hua, Bingxi, Zhang, Qingfeng, Guan, Beibei, Wang, Jifeng, Zeng, Xuemei, Wang, Kebang, Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603261/
https://www.ncbi.nlm.nih.gov/pubmed/31263234
http://dx.doi.org/10.1038/s41598-019-45913-6

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