Exercise training increases GAD65 expression, restores the depressed GABA(A) receptor function within the PVN and reduces sympathetic modulation in hypertension

GABAergic inhibitory input within the paraventricular hypothalamic nucleus (PVN) plays a key role in restraining sympathetic outflow. Although experimental evidence has shown depressed GABA(A) receptor function plus sympathoexcitation in hypertension and augmented GABA levels with reduced sympatheti...

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Detalles Bibliográficos
Autores principales: Ferreira‐Junior, Nilson C., Ruggeri, Adriana, Silva, Sebastião D., Zampieri, Thais T., Ceroni, Alexandre, Michelini, Lisete C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603325/
https://www.ncbi.nlm.nih.gov/pubmed/31264387
http://dx.doi.org/10.14814/phy2.14107

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