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Exercise training increases GAD65 expression, restores the depressed GABA(A) receptor function within the PVN and reduces sympathetic modulation in hypertension
GABAergic inhibitory input within the paraventricular hypothalamic nucleus (PVN) plays a key role in restraining sympathetic outflow. Although experimental evidence has shown depressed GABA(A) receptor function plus sympathoexcitation in hypertension and augmented GABA levels with reduced sympatheti...
Autores principales: | Ferreira‐Junior, Nilson C., Ruggeri, Adriana, Silva, Sebastião D., Zampieri, Thais T., Ceroni, Alexandre, Michelini, Lisete C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603325/ https://www.ncbi.nlm.nih.gov/pubmed/31264387 http://dx.doi.org/10.14814/phy2.14107 |
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