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Asymmetric Division Gene Neurl2 Mediates Twist2 Regulation of Self-Renewal of Mouse Lewis Lung Cancer Stem Cells

Cancer stem cells (CSCs) play an important role in tumor development. While Epithelial-Mesenchymal Transition (EMT) has been shown to promote CSC self-renewal, underlying mechanisms are unclear. Here we identified and characterized the requirement of twist2, the EMT transcription factor, for the reg...

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Detalles Bibliográficos
Autores principales: Liu, Doudou, Xing, H. Rosie, Liu, Yongli, Sun, Zhiwei, Ye, Ting, Li, Jingyuan, Wang, Jianyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603408/
https://www.ncbi.nlm.nih.gov/pubmed/31293641
http://dx.doi.org/10.7150/jca.31553