A Schiff Base Fluorescence Enhancement Probe for Fe(III) and Its Sensing Applications in Cancer Cells

We report a new Schiff base fluorescent probe which senses ferric ion, Fe(III), with a significant fluorescence enhancement response. The probe showed high sensitivity (0.8 ppb), and fast response time (<10 s) of Fe(III) in aqueous media. In addition, the probe showed the ability to sense Fe(III)...

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Detalles Bibliográficos
Autores principales: Kim, Na Hee, Lee, Junho, Park, Sungnam, Jung, Junyang, Kim, Dokyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603573/
https://www.ncbi.nlm.nih.gov/pubmed/31159266
http://dx.doi.org/10.3390/s19112500
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author Kim, Na Hee
Lee, Junho
Park, Sungnam
Jung, Junyang
Kim, Dokyoung
author_facet Kim, Na Hee
Lee, Junho
Park, Sungnam
Jung, Junyang
Kim, Dokyoung
author_sort Kim, Na Hee
collection PubMed
description We report a new Schiff base fluorescent probe which senses ferric ion, Fe(III), with a significant fluorescence enhancement response. The probe showed high sensitivity (0.8 ppb), and fast response time (<10 s) of Fe(III) in aqueous media. In addition, the probe showed the ability to sense Fe(III) in a HeLa cancer cell line, with very low cytotoxicity. As a new bio-imaging probe for Fe(III), it gave bright fluorescent images in confocal laser scanning microscopy (CLSM).
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spelling pubmed-66035732019-07-17 A Schiff Base Fluorescence Enhancement Probe for Fe(III) and Its Sensing Applications in Cancer Cells Kim, Na Hee Lee, Junho Park, Sungnam Jung, Junyang Kim, Dokyoung Sensors (Basel) Communication We report a new Schiff base fluorescent probe which senses ferric ion, Fe(III), with a significant fluorescence enhancement response. The probe showed high sensitivity (0.8 ppb), and fast response time (<10 s) of Fe(III) in aqueous media. In addition, the probe showed the ability to sense Fe(III) in a HeLa cancer cell line, with very low cytotoxicity. As a new bio-imaging probe for Fe(III), it gave bright fluorescent images in confocal laser scanning microscopy (CLSM). MDPI 2019-05-31 /pmc/articles/PMC6603573/ /pubmed/31159266 http://dx.doi.org/10.3390/s19112500 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Kim, Na Hee
Lee, Junho
Park, Sungnam
Jung, Junyang
Kim, Dokyoung
A Schiff Base Fluorescence Enhancement Probe for Fe(III) and Its Sensing Applications in Cancer Cells
title A Schiff Base Fluorescence Enhancement Probe for Fe(III) and Its Sensing Applications in Cancer Cells
title_full A Schiff Base Fluorescence Enhancement Probe for Fe(III) and Its Sensing Applications in Cancer Cells
title_fullStr A Schiff Base Fluorescence Enhancement Probe for Fe(III) and Its Sensing Applications in Cancer Cells
title_full_unstemmed A Schiff Base Fluorescence Enhancement Probe for Fe(III) and Its Sensing Applications in Cancer Cells
title_short A Schiff Base Fluorescence Enhancement Probe for Fe(III) and Its Sensing Applications in Cancer Cells
title_sort schiff base fluorescence enhancement probe for fe(iii) and its sensing applications in cancer cells
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603573/
https://www.ncbi.nlm.nih.gov/pubmed/31159266
http://dx.doi.org/10.3390/s19112500
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