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Urinary TERT promoter mutations as non-invasive biomarkers for the comprehensive detection of urothelial cancer
BACKGROUND: Recurrent mutations in the promoter of the telomerase reverse transcriptase (TERT) gene (C228T and C250T) detected in tumours and cells shed into urine of urothelial cancer (UC) patients are putative biomarkers for UC detection and monitoring. However, the possibility of detecting these...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603852/ https://www.ncbi.nlm.nih.gov/pubmed/31122840 http://dx.doi.org/10.1016/j.ebiom.2019.05.004 |