Cargando…

Lipid Metabolism in Late-Onset Alzheimer’s Disease Differs from Patients Presenting with Other Dementia Phenotypes

Abnormal cerebrospinal fluid (CSF) levels of β-amyloid peptides (Aβ(42)) and Tau and cognitive decline are typical characteristics of Alzheimer’s disease (AD). Since dysregulation in lipid metabolism accompanies abnormal amyloid formation, we quantified glycerophospholipids (GP) and sphingolipids (S...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sarrafpour, Syena, Ormseth, Cora, Chiang, Abby, Arakaki, Xianghong, Harrington, Michael, Fonteh, Alfred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603882/ https://www.ncbi.nlm.nih.gov/pubmed/31195602 http://dx.doi.org/10.3390/ijerph16111995

Ejemplares similares

Sphingolipid Metabolism Correlates with Cerebrospinal Fluid Beta Amyloid Levels in Alzheimer’s Disease
por: Fonteh, Alfred N., et al.
Publicado: (2015)

Accumulation of Cerebrospinal Fluid Glycerophospholipids and Sphingolipids in Cognitively Healthy Participants With Alzheimer’s Biomarkers Precedes Lipolysis in the Dementia Stage
por: Fonteh, Alfred N., et al.
Publicado: (2020)

Polyunsaturated Fatty Acid Composition of Cerebrospinal Fluid Fractions Shows Their Contribution to Cognitive Resilience of a Pre-symptomatic Alzheimer’s Disease Cohort
por: Fonteh, Alfred N., et al.
Publicado: (2020)

Human Cerebrospinal Fluid Fatty Acid Levels Differ between Supernatant Fluid and Brain-Derived Nanoparticle Fractions, and Are Altered in Alzheimer's Disease
por: Fonteh, Alfred N., et al.
Publicado: (2014)

Plasma Lipolysis and Changes in Plasma and Cerebrospinal Fluid Signaling Lipids Reveal Abnormal Lipid Metabolism in Chronic Migraine
por: Castor, Katherine, et al.
Publicado: (2021)

Alpha desynchronization during simple working memory unmasks pathological aging in cognitively healthy individuals
por: Arakaki, Xianghong, et al.
Publicado: (2019)

Compromised Behavior and Gamma Power During Working Memory in Cognitively Healthy Individuals With Abnormal CSF Amyloid/Tau
por: Rochart, Roger, et al.
Publicado: (2020)

Na,K-ATPase alpha isoforms at the blood-cerebrospinal fluid-trigeminal nerve and blood-retina interfaces in the rat
por: Arakaki, Xianghong, et al.
Publicado: (2013)

Severe Headache or Migraine History Is Inversely Correlated With Dietary Sodium Intake: NHANES 1999–2004
por: Pogoda, Janice M., et al.
Publicado: (2016)

Involvement of Lipids in Alzheimer’s Disease Pathology and Potential Therapies
por: Chew, Hannah, et al.
Publicado: (2020)

Development of the CHARIOT Research Register for the Prevention of Alzheimer’s Dementia and Other Late Onset Neurodegenerative Diseases
por: Larsen, Mark E., et al.
Publicado: (2015)

The Implication of the Brain Insulin Receptor in Late Onset Alzheimer’s Disease Dementia
por: Folch, Jaume, et al.
Publicado: (2018)

The Involvement of Peripheral and Brain Insulin Resistance in Late Onset Alzheimer’s Dementia
por: Folch, Jaume, et al.
Publicado: (2019)

Alpha desynchronization/synchronization during working memory testing is compromised in acute mild traumatic brain injury (mTBI)
por: Arakaki, Xianghong, et al.
Publicado: (2018)

Effects of ApoE genotype on clinical phenotypes in early‐onset and late‐onset Alzheimer's disease in China: Data from the PUMCH dementia cohort
por: Dong, Liling, et al.
Publicado: (2021)

White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease
por: Klosinski, Lauren P., et al.
Publicado: (2015)

Executive Function Changes before Memory in Preclinical Alzheimer’s Pathology: A Prospective, Cross-Sectional, Case Control Study
por: Harrington, Michael G., et al.
Publicado: (2013)

Exploring prior diseases associated with incident late-onset Alzheimer’s disease dementia
por: Liao, Jung-Yu, et al.
Publicado: (2020)

Antibiotics for Spinal Cord Stimulation Trials and Implants: A Survey Analysis of Practice Patterns
por: Sarrafpour, Syena, et al.
Publicado: (2021)

Endogenous Na(+), K(+)-ATPase inhibitors and CSF [Na(+)] contribute to migraine formation
por: Gross, Noah B., et al.
Publicado: (2019)

Early Life Stress and Epigenetics in Late-onset Alzheimer’s Dementia: A Systematic Review
por: Lemche, Erwin
Publicado: (2018)

ABCA1‐Mediated Cholesterol Efflux Capacity to Cerebrospinal Fluid Is Reduced in Patients With Mild Cognitive Impairment and Alzheimer's Disease
por: Yassine, Hussein N., et al.
Publicado: (2016)

Task switching reveals abnormal brain-heart electrophysiological signatures in cognitively healthy individuals with abnormal CSF amyloid/tau, a pilot study
por: Arechavala, Rebecca Johnson, et al.
Publicado: (2021)

Caregiving in Alzheimer’s and Other Dementias
por: Horien, Corey
Publicado: (2016)

Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease
por: Elahi, Fanny M., et al.
Publicado: (2017)

Evidence that blood–CSF barrier transport, but not inflammatory biomarkers, change in migraine, while CSF sVCAM1 associates with migraine frequency and CSF fibrinogen
por: Cowan, Robert P., et al.
Publicado: (2021)

Genetics of Early-Onset Alzheimer Dementia
por: Rademakers, Rosa, et al.
Publicado: (2003)

A Comparison of Behavioral and Psychological Symptoms of Dementia (BPSD) and BPSD Sub-Syndromes in Early-Onset and Late-Onset Alzheimer’s Disease
por: Altomari, Natalia, et al.
Publicado: (2022)

Classifying late-onset dementia with MRI: Is arteriosclerotic brain degeneration the most common cause of Alzheimer’s syndrome?
por: Henry-Feugeas, Marie Cécile, et al.
Publicado: (2008)

Quality of Life in Advanced Dementia with Late Onset, Young Onset, and Very Young Onset
por: Hartmann, Julia, et al.
Publicado: (2021)

Very late-onset behavioral variant frontotemporal dementia
por: Guimarães, Henrique Cerqueira, et al.
Publicado: (2013)

Chlamydia pneumoniae: An Etiologic Agent for Late-Onset Dementia
por: Balin, Brian J., et al.
Publicado: (2018)

Late-onset epilepsy and subsequent increased risk of dementia
por: Tsai, Zhi-Ren, et al.
Publicado: (2021)

Editorial: Lipid Metabolism and Transport in CNS Health and Disease
por: Bruce, Kimberley D., et al.
Publicado: (2021)

Late onset Alzheimer’s disease in older people
por: Isik, Ahmet Turan
Publicado: (2010)

Too narrow and too broad: Differentiating late-onset dementia from its historical entanglement with Alzheimer’s disease
por: Moseholm, Kristine F., et al.
Publicado: (2021)

Aspirin and Risk of Dementia in Patients with Late-Onset Depression: A Population-Based Cohort Study
por: Yang, Ya-Hsu, et al.
Publicado: (2020)

Stronger implicit interference in cognitively healthy older participants with higher risk of Alzheimer's disease
por: Hung, Shao‐Min, et al.
Publicado: (2022)

How Do Persons with Young and Late Onset Dementia Die?
por: Roβmeier, Carola, et al.
Publicado: (2021)

Suicidal Ideations and Behavior in Patients With Young and Late Onset Dementia
por: Ortner, Marion, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ori28orohigno7vbp9ikqsscq0