Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans

BACKGROUND: Genetic diversity is known to confer survival advantage in many species across the tree of life. Here, we hypothesize that such pattern applies to humans as well and could be a result of higher fitness in individuals with higher genomic heterozygosity. RESULTS: We use healthy aging as a...

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Detalles Bibliográficos
Autores principales: Xu, Ke, Kosoy, Roman, Shameer, Khader, Kumar, Sudhir, Liu, Li, Readhead, Ben, Belbin, Gillian M., Lee, Hao-Chih, Chen, Rong, Dudley, Joel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604157/
https://www.ncbi.nlm.nih.gov/pubmed/31266448
http://dx.doi.org/10.1186/s12863-019-0758-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604157/
https://www.ncbi.nlm.nih.gov/pubmed/31266448
http://dx.doi.org/10.1186/s12863-019-0758-4

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