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CFTR regulates B cell activation and lymphoid follicle development
BACKGROUND: Cystic fibrosis (CF) is an inherited disorder caused by mutations in the CF transmembrane conductance regulator (CFTR) gene that promotes persistent lung infection and inflammation and progressive loss of lung function. Patients with CF have increased lung lymphoid follicles (LFs) and B...
Autores principales: | Polverino, Francesca, Lu, Bao, Quintero, Joselyn Rojas, Vargas, Sara O., Patel, Avignat S., Owen, Caroline A., Gerard, Norma P., Gerard, Craig, Cernadas, Manuela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604167/ https://www.ncbi.nlm.nih.gov/pubmed/31262295 http://dx.doi.org/10.1186/s12931-019-1103-1 |
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