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Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines
BACKGROUND: Patient-derived xenograft (PDX) models are in vivo models of human cancer that have been used for translational cancer research and therapy selection for individual patients. The Jackson Laboratory (JAX) PDX resource comprises 455 models originating from 34 different primary sites (as of...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604205/ https://www.ncbi.nlm.nih.gov/pubmed/31262303 http://dx.doi.org/10.1186/s12920-019-0551-2 |