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Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines

BACKGROUND: Patient-derived xenograft (PDX) models are in vivo models of human cancer that have been used for translational cancer research and therapy selection for individual patients. The Jackson Laboratory (JAX) PDX resource comprises 455 models originating from 34 different primary sites (as of...

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Detalles Bibliográficos
Autores principales:	Woo, Xing Yi, Srivastava, Anuj, Graber, Joel H., Yadav, Vinod, Sarsani, Vishal Kumar, Simons, Al, Beane, Glen, Grubb, Stephen, Ananda, Guruprasad, Liu, Rangjiao, Stafford, Grace, Chuang, Jeffrey H., Airhart, Susan D., Karuturi, R. Krishna Murthy, George, Joshy, Bult, Carol J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604205/ https://www.ncbi.nlm.nih.gov/pubmed/31262303 http://dx.doi.org/10.1186/s12920-019-0551-2

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