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From bench to bedside: in vitro and in vivo evaluation of a neonate-focused nebulized surfactant delivery strategy

BACKGROUND: Non-invasive delivery of nebulized surfactant has been a neonatology long-pursued goal. Nevertheless, the clinical efficacy of nebulized surfactant remains inconclusive, in part, due to the great technical challenges of depositing nebulized drugs in the lungs of preterm infants. The aim...

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Detalles Bibliográficos
Autores principales: Bianco, F., Ricci, F., Catozzi, C., Murgia, X., Schlun, M., Bucholski, A., Hetzer, U., Bonelli, S., Lombardini, M., Pasini, E., Nutini, M., Pertile, M., Minocchieri, S., Simonato, M., Rosa, B., Pieraccini, G., Moneti, G., Lorenzini, L., Catinella, S., Villetti, G., Civelli, M., Pioselli, B., Cogo, P., Carnielli, V., Dani, C., Salomone, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604359/
https://www.ncbi.nlm.nih.gov/pubmed/31266508
http://dx.doi.org/10.1186/s12931-019-1096-9