Mucin 17 inhibits the progression of human gastric cancer by limiting inflammatory responses through a MYH9-p53-RhoA regulatory feedback loop

BACKGROUND: Mucins are key components of the mucosal barrier in the stomach that protects epithelia from carcinogenic effects of chronic inflammation. Analysis of The Cancer Genome Atlas database indicated that mucin-17 (MUC17) was more highly expressed in gastric cancer (GC) specimens, with favoura...

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Detalles Bibliográficos
Autores principales: Yang, Bing, Wu, Aiwen, Hu, Yingqi, Tao, Cuijian, Wang, Ji Ming, Lu, Youyong, Xing, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604468/
https://www.ncbi.nlm.nih.gov/pubmed/31262330
http://dx.doi.org/10.1186/s13046-019-1279-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604468/
https://www.ncbi.nlm.nih.gov/pubmed/31262330
http://dx.doi.org/10.1186/s13046-019-1279-8

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