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An NFκB Activity Calculator to Delineate Signaling Crosstalk: Type I and II Interferons Enhance NFκB via Distinct Mechanisms
Nuclear factor kappa B (NFκB) is a transcription factor that controls inflammation and cell survival. In clinical histology, elevated NFκB activity is a hallmark of poor prognosis in inflammatory disease and cancer, and may be the result of a combination of diverse micro-environmental constituents....
Autores principales: | Mitchell, Simon, Mercado, Ellen L., Adelaja, Adewunmi, Ho, Jessica Q., Cheng, Quen J., Ghosh, Gourisankar, Hoffmann, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604663/ https://www.ncbi.nlm.nih.gov/pubmed/31293585 http://dx.doi.org/10.3389/fimmu.2019.01425 |
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