Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Ca(v)3.2 T-type voltage-gated calcium channels and Ca(2+) influx

BACKGROUND: Administration of amplitude modulated 27·12 MHz radiofrequency electromagnetic fields (AM RF EMF) by means of a spoon-shaped applicator placed on the patient's tongue is a newly approved treatment for advanced hepatocellular carcinoma (HCC). The mechanism of action of tumour-specifi...

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Detalles Bibliográficos
Autores principales: Jimenez, Hugo, Wang, Minghui, Zimmerman, Jacquelyn W., Pennison, Michael J., Sharma, Sambad, Surratt, Trevor, Xu, Zhi-Xiang, Brezovich, Ivan, Absher, Devin, Myers, Richard M., DeYoung, Barry, Caudell, David L., Chen, Dongquan, Lo, Hui-Wen, Lin, Hui-Kuan, Godwin, Dwayne W., Olivier, Michael, Ghanekar, Anand, Chen, Kui, Miller, Lance D., Gong, Yijian, Capstick, Myles, D'Agostino, Ralph B., Munden, Reginald, Merle, Philippe, Barbault, Alexandre, Blackstock, Arthur W., Bonkovsky, Herbert L., Yang, Guang-Yu, Jin, Guangxu, Liu, Liang, Zhang, Wei, Watabe, Kounosuke, Blackman, Carl F., Pasche, Boris C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604666/
https://www.ncbi.nlm.nih.gov/pubmed/31160272
http://dx.doi.org/10.1016/j.ebiom.2019.05.034

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