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Ethanol extracts of Allium sp. regulate cyclooxygenase-2 and E-cadherin expression in gastric cancer MKN74 cell line and enhance doxorubicin toxicity

BACKGROUND: Gastric cancer (GC) remains one of the leading causes of cancer-related death. Its aetiology is multifactorial, but the major risk factor is a high in salt diet. During gastric carcinogenesis, cadherin-1 (CDH1) down-expression and cyclooxygenase 2 (COX2) overexpression may be observed. T...

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Detalles Bibliográficos
Autores principales: Korga, Agnieszka, Ostrowska, Marta, Iwan, Magdalena, Skierucha, Małgorzata, Józefczyk, Aleksandra, Pawłowski, Piotr, Dudka, Jarosław, Maciejewski, Ryszard, Sitarz, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Open Academia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604903/
https://www.ncbi.nlm.nih.gov/pubmed/31297043
http://dx.doi.org/10.29219/fnr.v63.3449