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Quinalizarin, a specific CK2 inhibitor, can reduce icotinib resistance in human lung adenocarcinoma cell lines

The abnormal activation of the downstream signaling pathways of epidermal growth factor receptor (EGFR) that are independent of EGFR, contribute to the acquisition of EGFR-tyrosine kinase inhibitor (TKI) resistance in non-small cell lung cancer (NSCLC). The serine/threonine protein kinase casein kin...

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Detalles Bibliográficos
Autores principales:	Li, Ke, Zhou, Fangzheng, Zhou, Yu, Zhang, Sheng, Li, Qianwen, Li, Zhenyu, Liu, Li, Wu, Gang, Meng, Rui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605624/ https://www.ncbi.nlm.nih.gov/pubmed/31173177 http://dx.doi.org/10.3892/ijmm.2019.4220

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