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Clinical significance of early recurrence of atrial fibrillation after cryoballoon vs. radiofrequency ablation—A propensity score matched analysis
OBJECTIVES: One of the mechanisms of early recurrence of atrial fibrillation (ERAF) after AF ablation is considered to be the inflammatory reaction of the atrial tissue. The aim of this study is to compare the clinical significance of ERAF at each stage for true AF recurrence between cryoballoon (CB...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605651/ https://www.ncbi.nlm.nih.gov/pubmed/31265482 http://dx.doi.org/10.1371/journal.pone.0219269 |
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author | Tokuda, Michifumi Yamashita, Seigo Matsuo, Seiichiro Kato, Mika Sato, Hidenori Oseto, Hirotsuna Okajima, Eri Ikewaki, Hidetsugu Yokoyama, Masaaki Isogai, Ryota Tokutake, Kenichi Yokoyama, Kenichi Narui, Ryohsuke Tanigawa, Shin-ichi Yoshimura, Michihiro Yamane, Teiichi |
author_facet | Tokuda, Michifumi Yamashita, Seigo Matsuo, Seiichiro Kato, Mika Sato, Hidenori Oseto, Hirotsuna Okajima, Eri Ikewaki, Hidetsugu Yokoyama, Masaaki Isogai, Ryota Tokutake, Kenichi Yokoyama, Kenichi Narui, Ryohsuke Tanigawa, Shin-ichi Yoshimura, Michihiro Yamane, Teiichi |
author_sort | Tokuda, Michifumi |
collection | PubMed |
description | OBJECTIVES: One of the mechanisms of early recurrence of atrial fibrillation (ERAF) after AF ablation is considered to be the inflammatory reaction of the atrial tissue. The aim of this study is to compare the clinical significance of ERAF at each stage for true AF recurrence between cryoballoon (CB) and radiofrequency (RF) ablation. METHODS: Among 798 paroxysmal AF patients who underwent an initial ablation, 460 patients (CB, n = 230; RF, n = 230) were selected by propensity score matching. Very ERAF (VERAF), ERAF-1M, ERAF-3M and true AF recurrence were defined as AF recurrence at 0–2, 3–30, 31–90 days and more than 90 days after the procedure, respectively. RESULTS: The patient characteristics of the two groups were similar. ERAF was observed 21% and 27% in the CB and RF groups, respectively. In both the CB and RF group, VERAF, ERAF-1M and ERAF-3M were more frequently observed in patients with true AF recurrence than in those without. In a multivariable analysis, ERAF-1M and ERAF-3M were found to be independent predictors of true AF recurrence in both the CB (P = 0.04 and P<0.001, respectively) and RF groups (P = 0.02 and P = 0.001, respectively). However, while VERAF was associated with true AF recurrence after RF ablation (P = 0.03), it was not associated with true AF recurrence after CB ablation (P = 0.19). CONCLUSION: The relationship between ERAF and true AF recurrence differed between the RF and CB ablation groups. While VERAF was associated with true AF recurrence after RF ablation, it was not a predictor of true AF recurrence after CB ablation. |
format | Online Article Text |
id | pubmed-6605651 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-66056512019-07-12 Clinical significance of early recurrence of atrial fibrillation after cryoballoon vs. radiofrequency ablation—A propensity score matched analysis Tokuda, Michifumi Yamashita, Seigo Matsuo, Seiichiro Kato, Mika Sato, Hidenori Oseto, Hirotsuna Okajima, Eri Ikewaki, Hidetsugu Yokoyama, Masaaki Isogai, Ryota Tokutake, Kenichi Yokoyama, Kenichi Narui, Ryohsuke Tanigawa, Shin-ichi Yoshimura, Michihiro Yamane, Teiichi PLoS One Research Article OBJECTIVES: One of the mechanisms of early recurrence of atrial fibrillation (ERAF) after AF ablation is considered to be the inflammatory reaction of the atrial tissue. The aim of this study is to compare the clinical significance of ERAF at each stage for true AF recurrence between cryoballoon (CB) and radiofrequency (RF) ablation. METHODS: Among 798 paroxysmal AF patients who underwent an initial ablation, 460 patients (CB, n = 230; RF, n = 230) were selected by propensity score matching. Very ERAF (VERAF), ERAF-1M, ERAF-3M and true AF recurrence were defined as AF recurrence at 0–2, 3–30, 31–90 days and more than 90 days after the procedure, respectively. RESULTS: The patient characteristics of the two groups were similar. ERAF was observed 21% and 27% in the CB and RF groups, respectively. In both the CB and RF group, VERAF, ERAF-1M and ERAF-3M were more frequently observed in patients with true AF recurrence than in those without. In a multivariable analysis, ERAF-1M and ERAF-3M were found to be independent predictors of true AF recurrence in both the CB (P = 0.04 and P<0.001, respectively) and RF groups (P = 0.02 and P = 0.001, respectively). However, while VERAF was associated with true AF recurrence after RF ablation (P = 0.03), it was not associated with true AF recurrence after CB ablation (P = 0.19). CONCLUSION: The relationship between ERAF and true AF recurrence differed between the RF and CB ablation groups. While VERAF was associated with true AF recurrence after RF ablation, it was not a predictor of true AF recurrence after CB ablation. Public Library of Science 2019-07-02 /pmc/articles/PMC6605651/ /pubmed/31265482 http://dx.doi.org/10.1371/journal.pone.0219269 Text en © 2019 Tokuda et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Tokuda, Michifumi Yamashita, Seigo Matsuo, Seiichiro Kato, Mika Sato, Hidenori Oseto, Hirotsuna Okajima, Eri Ikewaki, Hidetsugu Yokoyama, Masaaki Isogai, Ryota Tokutake, Kenichi Yokoyama, Kenichi Narui, Ryohsuke Tanigawa, Shin-ichi Yoshimura, Michihiro Yamane, Teiichi Clinical significance of early recurrence of atrial fibrillation after cryoballoon vs. radiofrequency ablation—A propensity score matched analysis |
title | Clinical significance of early recurrence of atrial fibrillation after cryoballoon vs. radiofrequency ablation—A propensity score matched analysis |
title_full | Clinical significance of early recurrence of atrial fibrillation after cryoballoon vs. radiofrequency ablation—A propensity score matched analysis |
title_fullStr | Clinical significance of early recurrence of atrial fibrillation after cryoballoon vs. radiofrequency ablation—A propensity score matched analysis |
title_full_unstemmed | Clinical significance of early recurrence of atrial fibrillation after cryoballoon vs. radiofrequency ablation—A propensity score matched analysis |
title_short | Clinical significance of early recurrence of atrial fibrillation after cryoballoon vs. radiofrequency ablation—A propensity score matched analysis |
title_sort | clinical significance of early recurrence of atrial fibrillation after cryoballoon vs. radiofrequency ablation—a propensity score matched analysis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605651/ https://www.ncbi.nlm.nih.gov/pubmed/31265482 http://dx.doi.org/10.1371/journal.pone.0219269 |
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