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Actin assembly and non-muscle myosin activity drive dendrite retraction in an UNC-6/Netrin dependent self-avoidance response

Dendrite growth is constrained by a self-avoidance response that induces retraction but the downstream pathways that balance these opposing mechanisms are unknown. We have proposed that the diffusible cue UNC-6(Netrin) is captured by UNC-40(DCC) for a short-range interaction with UNC-5 to trigger se...

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Detalles Bibliográficos
Autores principales: Sundararajan, Lakshmi, Smith, Cody J., Watson, Joseph D., Millis, Bryan A., Tyska, Matthew J., Miller, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605669/
https://www.ncbi.nlm.nih.gov/pubmed/31220078
http://dx.doi.org/10.1371/journal.pgen.1008228