Proliferative memory SAMHD1(low) CD4(+) T cells harbour high levels of HIV-1 with compartmentalized viral populations

We previously reported the presence of memory CD4(+) T cells that express low levels of SAMHD1 (SAMHD1(low)) in peripheral blood and lymph nodes from both HIV-1 infected and uninfected individuals. These cells are enriched in Th17 and Tfh subsets, two populations known to be preferentially targeted...

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Detalles Bibliográficos
Autores principales: Hani, Lylia, Chaillon, Antoine, Nere, Marie-Laure, Ruffin, Nicolas, Alameddine, Joudy, Salmona, Maud, Lopez Zaragoza, José-Luiz, Smith, Davey M., Schwartz, Olivier, Lelièvre, Jean-Daniel, Delaugerre, Constance, Lévy, Yves, Seddiki, Nabila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605680/
https://www.ncbi.nlm.nih.gov/pubmed/31220191
http://dx.doi.org/10.1371/journal.ppat.1007868

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