A microRNA-24-to-secretagogin regulatory pathway mediates cholesterol-induced inhibition of insulin secretion

Hypercholesterolemia is a key factor leading to β-cell dysfunction, but its underlying mechanisms remain unclear. Secretagogin (Scgn), a Ca(2+) sensor protein that is expressed at high levels in the islets, has been shown to play a key role in regulating insulin secretion through effects on the solu...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Jing, Lv, Yuncheng, Zhao, Zhibo, Li, Wu, Xiang, Sunmin, Zhou, Lingzhi, Gao, Anbo, Yan, Bin, Ou, Lingling, Ling, Hong, Xiao, Xinhua, Liu, Jianghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605698/
https://www.ncbi.nlm.nih.gov/pubmed/31173188
http://dx.doi.org/10.3892/ijmm.2019.4224

Ejemplares similares

Ejemplares similares