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Hlf marks the developmental pathway for hematopoietic stem cells but not for erythro-myeloid progenitors

Before the emergence of hematopoietic stem cells (HSCs), lineage-restricted progenitors, such as erythro-myeloid progenitors (EMPs), are detected in the embryo or in pluripotent stem cell cultures in vitro. Although both HSCs and EMPs are derived from hemogenic endothelium, it remains unclear how an...

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Detalles Bibliográficos
Autores principales: Yokomizo, Tomomasa, Watanabe, Naoki, Umemoto, Terumasa, Matsuo, Junichi, Harai, Ryota, Kihara, Yoshihiko, Nakamura, Eri, Tada, Norihiro, Sato, Tomohiko, Takaku, Tomoiku, Shimono, Akihiko, Takizawa, Hitoshi, Nakagata, Naomi, Mori, Seiichi, Kurokawa, Mineo, Tenen, Daniel G., Osato, Motomi, Suda, Toshio, Komatsu, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605751/
https://www.ncbi.nlm.nih.gov/pubmed/31076455
http://dx.doi.org/10.1084/jem.20181399