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Hlf marks the developmental pathway for hematopoietic stem cells but not for erythro-myeloid progenitors
Before the emergence of hematopoietic stem cells (HSCs), lineage-restricted progenitors, such as erythro-myeloid progenitors (EMPs), are detected in the embryo or in pluripotent stem cell cultures in vitro. Although both HSCs and EMPs are derived from hemogenic endothelium, it remains unclear how an...
Autores principales: | Yokomizo, Tomomasa, Watanabe, Naoki, Umemoto, Terumasa, Matsuo, Junichi, Harai, Ryota, Kihara, Yoshihiko, Nakamura, Eri, Tada, Norihiro, Sato, Tomohiko, Takaku, Tomoiku, Shimono, Akihiko, Takizawa, Hitoshi, Nakagata, Naomi, Mori, Seiichi, Kurokawa, Mineo, Tenen, Daniel G., Osato, Motomi, Suda, Toshio, Komatsu, Norio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605751/ https://www.ncbi.nlm.nih.gov/pubmed/31076455 http://dx.doi.org/10.1084/jem.20181399 |
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