c-Myc steers translation in lymphoma

Members of the MYC family of oncogenes are master regulators of mRNA translation. In this issue of JEM, Singh et al. (https://doi.org/10.1084/jem.20181726) demonstrate that c-Myc governs protein synthesis in lymphoma cells by interfering with SRSF1- and RBM42-mediated suppression of mRNA translation...

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Detalles Bibliográficos
Autores principales: Cargnello, Marie, Topisirovic, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605756/
https://www.ncbi.nlm.nih.gov/pubmed/31209069
http://dx.doi.org/10.1084/jem.20190721
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author Cargnello, Marie
Topisirovic, Ivan
author_facet Cargnello, Marie
Topisirovic, Ivan
author_sort Cargnello, Marie
collection PubMed
description Members of the MYC family of oncogenes are master regulators of mRNA translation. In this issue of JEM, Singh et al. (https://doi.org/10.1084/jem.20181726) demonstrate that c-Myc governs protein synthesis in lymphoma cells by interfering with SRSF1- and RBM42-mediated suppression of mRNA translation and by altering selection of translation initiation sites.
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spelling pubmed-66057562020-01-01 c-Myc steers translation in lymphoma Cargnello, Marie Topisirovic, Ivan J Exp Med News Members of the MYC family of oncogenes are master regulators of mRNA translation. In this issue of JEM, Singh et al. (https://doi.org/10.1084/jem.20181726) demonstrate that c-Myc governs protein synthesis in lymphoma cells by interfering with SRSF1- and RBM42-mediated suppression of mRNA translation and by altering selection of translation initiation sites. Rockefeller University Press 2019-07-01 2019-06-17 /pmc/articles/PMC6605756/ /pubmed/31209069 http://dx.doi.org/10.1084/jem.20190721 Text en © 2019 Cargnello and Topisirovic http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle News
Cargnello, Marie
Topisirovic, Ivan
c-Myc steers translation in lymphoma
title c-Myc steers translation in lymphoma
title_full c-Myc steers translation in lymphoma
title_fullStr c-Myc steers translation in lymphoma
title_full_unstemmed c-Myc steers translation in lymphoma
title_short c-Myc steers translation in lymphoma
title_sort c-myc steers translation in lymphoma
topic News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605756/
https://www.ncbi.nlm.nih.gov/pubmed/31209069
http://dx.doi.org/10.1084/jem.20190721
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AT topisirovicivan cmycsteerstranslationinlymphoma

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