Detection of a novel panel of somatic mutations in plasma cell-free DNA and its diagnostic value in hepatocellular carcinoma

Background/aims: Circulating cell-free DNA (cfDNA) contains tumor-specific alterations and could potentially serve as “liquid biopsy”. The study was to identify a novel panel of hepatocellular carcinoma (HCC)-specific mutations in plasma cfDNA and to assess its value in the diagnosis of HCC. Materia...

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Detalles Bibliográficos
Autores principales: Xiong, Yu, Xie, Cheng-Rong, Zhang, Sheng, Chen, Jin, Yin, Zhen-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605764/
https://www.ncbi.nlm.nih.gov/pubmed/31303788
http://dx.doi.org/10.2147/CMAR.S197455

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