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Intrinsic checkpoint deficiency during cell cycle re-entry from quiescence

To maintain tissue homeostasis, cells transition between cell cycle quiescence and proliferation. An essential G1 process is minichromosome maintenance complex (MCM) loading at DNA replication origins to prepare for S phase, known as origin licensing. A p53-dependent origin licensing checkpoint norm...

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Detalles Bibliográficos
Autores principales:	Matson, Jacob Peter, House, Amy M., Grant, Gavin D., Wu, Huaitong, Perez, Joanna, Cook, Jeanette Gowen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605788/ https://www.ncbi.nlm.nih.gov/pubmed/31186278 http://dx.doi.org/10.1083/jcb.201902143

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