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Repair of nuclear ruptures requires barrier-to-autointegration factor

Cell nuclei rupture following exposure to mechanical force and/or upon weakening of nuclear integrity, but nuclear ruptures are repairable. Barrier-to-autointegration factor (BAF), a small DNA-binding protein, rapidly localizes to nuclear ruptures; however, its role at these rupture sites is unknown...

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Detalles Bibliográficos
Autores principales: Halfmann, Charles T., Sears, Rhiannon M., Katiyar, Aditya, Busselman, Brook W., Aman, London K., Zhang, Qiao, O’Bryan, Christopher S., Angelini, Thomas E., Lele, Tanmay P., Roux, Kyle J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605789/
https://www.ncbi.nlm.nih.gov/pubmed/31147383
http://dx.doi.org/10.1083/jcb.201901116

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