XLF extends its range from DNA repair to replication

The close interplay between DNA replication and repair is underscored by a report from Chen et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201808134) in this issue. The authors demonstrate that the non-homologous end-joining factor XLF promotes the stability of replication forks.

Detalles Bibliográficos
Autores principales: Gonzalez-Rodriguez, Yanira, Bunting, Samuel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605802/
https://www.ncbi.nlm.nih.gov/pubmed/31189608
http://dx.doi.org/10.1083/jcb.201905221
Descripción
Sumario:The close interplay between DNA replication and repair is underscored by a report from Chen et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201808134) in this issue. The authors demonstrate that the non-homologous end-joining factor XLF promotes the stability of replication forks.

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