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Curcumin-loaded PEG-PDLLA nanoparticles for attenuating palmitate-induced oxidative stress and cardiomyocyte apoptosis through AMPK pathway

Curcumin (CUR) has the ability to attenuate oxidative stress in the myocardium and to protect the myocardium from lipotoxic injury owing to its lipid-reducing properties. However, the use of CUR is limited due to its hydrophobicity and instability. In this study, CUR-loaded nanoparticles (CUR NPs) w...

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Detalles Bibliográficos
Autores principales: Zhang, Jingyi, Wang, Ying, Bao, Cuiyu, Liu, Tao, Li, Shuai, Huang, Jiaxi, Wan, Ying, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605976/
https://www.ncbi.nlm.nih.gov/pubmed/31173176
http://dx.doi.org/10.3892/ijmm.2019.4228