Combined α-programmed death-1 monoclonal antibody blockade and fractionated radiation therapy reduces tumor growth in mouse EL4 lymphoma

The programmed death (PD) pathway is frequently present in the tumor microenvironment (TME) and suppresses tumor immunity by inhibiting the activity of tumor-infiltrating lymphocytes (TILs), particularly, CD8(+) lymphocytes. PD immunotherapy involves stimulation of the immune response in the region...

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Detalles Bibliográficos
Autores principales: Lin, Xiuyun, Zeng, Tao, Xiong, Jiani, Zhang, Qiong, Jiang, Pan, Li, Xiufeng, Lin, Shuchun, Xu, Qianqian, Weng, Huanjiao, Lai, Haichun, Gong, Huichun, Lin, Jinxiang, Cheng, Niangmei, Tian, Xinling, Xu, Yunlu, Fang, Shubin, Jin, Rong, Chen, Zhiwei, Yang, Jianbo, Morton, Luke, Yueh, Bevan, Lin, Jizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605991/
https://www.ncbi.nlm.nih.gov/pubmed/30572778
http://dx.doi.org/10.1080/15384047.2018.1550569

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