M2-like tumor-associated macrophages-secreted EGF promotes epithelial ovarian cancer metastasis via activating EGFR-ERK signaling and suppressing lncRNA LIMT expression

Background: Ovarian cancer (OC) is the gynecologic malignant tumor with high mortality. Accumulating evidence indicates that M2-like tumor-associated macrophages (TAMs) can secret EGF to participate in ovarian cancer growth, migration, and metastasis. An EGF-downregulated lncRNA, LIMT (lncRNA inhibi...

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Detalles Bibliográficos
Autores principales: Zeng, Xiang-Yang, Xie, Hui, Yuan, Jing, Jiang, Xiao-Yan, Yong, Jia-Hui, Zeng, Da, Dou, Ying-Yu, Xiao, Song-Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606001/
https://www.ncbi.nlm.nih.gov/pubmed/31062668
http://dx.doi.org/10.1080/15384047.2018.1564567

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