Cargando…

Pancreatic acinar cell carcinoma is associated with BRCA2 germline mutations: a case report and literature review

Acinar cell carcinoma (ACC) is a rare pancreatic neoplasm with dismal prognosis. Insights into the molecular basis of ACC can pave the way for the application of more effective, personalized therapies and detection of patients with hereditary predisposition. Molecular analysis revealed a germline BR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kryklyva, Valentyna, Haj Mohammad, Nadia, Morsink, Folkert H.M., Ligtenberg, Marjolijn J.L., Offerhaus, G. Johan A., Nagtegaal, Iris D., de Leng, Wendy W.J., Brosens, Lodewijk A.A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Bedside-to-Bench Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606020/ https://www.ncbi.nlm.nih.gov/pubmed/31002019 http://dx.doi.org/10.1080/15384047.2019.1595274

Ejemplares similares

Dramatic response to local radiotherapy in a refractory metastatic mediastinal yolk sac tumor patient harboring a germline BRCA2 frameshift mutation: a case report
por: Cheng, Xi, et al.
Publicado: (2022)

Endovascular interventions for central vein stenosis
por: Agarwal, Anil K.
Publicado: (2015)

Current progress in ABO-incompatible kidney transplantation
por: Koo, Tai Yeon, et al.
Publicado: (2015)

Mismatch repair deficiency in early‐onset duodenal, ampullary, and pancreatic carcinomas is a strong indicator for a hereditary defect
por: Kryklyva, Valentyna, et al.
Publicado: (2021)

RNA sequencing of the nephron transcriptome: a technical note
por: Lee, Jae Wook
Publicado: (2015)

Organ-on-a-chip and the kidney
por: Kim, Sejoong, et al.
Publicado: (2015)

Neuro-tracing approach to study kidney innervation: a technical note
por: Lee, Sanghee, et al.
Publicado: (2017)

Messenger RNA vaccines against SARS-CoV-2
por: Topol, Eric J.
Publicado: (2021)

A novel BRCA2 mutation in prostate cancer sensitive to combined radiotherapy and androgen deprivation therapy
por: Liu, Qiuli, et al.
Publicado: (2018)

HIF2A germline–mutation-induced polycythemia in a patient with VHL-associated renal-cell carcinoma
por: Liu, Qiuli, et al.
Publicado: (2017)

Durable response to palbociclib and letrozole in ovarian cancer with CDKN2A loss
por: Frisone, Daniele, et al.
Publicado: (2019)

Discovery of a rare GKAP1-NTRK2 fusion in a pediatric low-grade glioma, leading to targeted treatment with TRK-inhibitor larotrectinib
por: Deland, Lily, et al.
Publicado: (2021)

Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer
por: Tsoli, Maria, et al.
Publicado: (2018)

Vemurafenib and panitumumab combination tailored therapy in BRAF-mutated metastatic colorectal cancer: A case report
por: Capalbo, Carlo, et al.
Publicado: (2014)

Is the skin a sanctuary for breast cancer cells during treatment with anti-HER2 antibodies?
por: Graziano, Vincenzo, et al.
Publicado: (2015)

Therapeutic approach guided by genetic alteration: Use of MTOR inhibitor in renal medullary carcinoma with loss of PTEN expression
por: Lipkin, Jacob S, et al.
Publicado: (2015)

Durable complete responses off all treatment in patients with metastatic malignant melanoma after sequential immunotherapy followed by a finite course of BRAF inhibitor therapy
por: Wyluda, Edward J, et al.
Publicado: (2015)

Metformin: a modulator of bevacizumab activity in cancer? A case report
por: Indraccolo, Stefano, et al.
Publicado: (2015)

Bortezomib-related neuropathy may mask CNS relapse in multiple myeloma: A call for diligence
por: Abid, Muhammad Bilal, et al.
Publicado: (2016)

How breast cancer chemotherapy increases the risk of leukemia: Thoughts about a case of diffuse large B-cell lymphoma and leukemia after breast cancer chemotherapy
por: Zhang, Bin, et al.
Publicado: (2016)

A new mutation of the CDH1 gene in a patient with an aggressive signet-ring cell carcinoma of the stomach
por: Caggiari, Laura, et al.
Publicado: (2017)

Effective treatment of aggressive fibromatosis with celecoxib guided by genetic testing
por: Yang, Shanshan, et al.
Publicado: (2017)

JAK2 V617F mutation in plasma cell-free DNA preceding clinically overt myelofibrosis: Implications for early diagnosis
por: Choi, Michael Y., et al.
Publicado: (2018)

CMTR1-ALK: an ALK fusion in a patient with no response to ALK inhibitor crizotinib
por: Du, Xue, et al.
Publicado: (2018)

A novel co-existing ZCCHC8-ROS1 and de-novo MET amplification dual driver in advanced lung adenocarcinoma with a good response to crizotinib
por: Zhu, You-cai, et al.
Publicado: (2018)

Successful treatment using apatinib in intractable brain edema: A case report and literatures review
por: Song, Yanqiu, et al.
Publicado: (2018)

Next-generation sequencing reveals mutational accordance between cell-free DNA from plasma, malignant pleural effusion and ascites and directs targeted therapy in a gastric cancer patient
por: Zhou, Shujuan, et al.
Publicado: (2018)

Ototoxicity in patients with invasive ductal breast cancer who were treated with docetaxel: report of two cases
por: Xuan, Liang, et al.
Publicado: (2020)

Unexpected favorable outcome to etoposide and cisplatin in a small cell lung cancer transformed patient: a case report
por: Xie, Zhanhong, et al.
Publicado: (2019)

De novo MET amplification promotes intrinsic resistance to first-generation EGFR tyrosine kinase inhibitors
por: Li, Jing-Wen, et al.
Publicado: (2019)

Nivolumab induced hyperprogressive disease in advanced esophageal squamous cell carcinoma
por: Sun, Dantong, et al.
Publicado: (2020)

Partial treatment response to capmatinib in MET-amplified metastatic intrahepatic cholangiocarcinoma: case report & review of literature
por: Lefler, Daniel S, et al.
Publicado: (2022)

Personalized functional profiling using ex-vivo patient-derived spheroids points out the potential of an antiangiogenic treatment in a patient with a metastatic lung atypical carcinoid
por: Kim, Hichul, et al.
Publicado: (2022)

Recent Advances in Celiac Disease from TTG to Gluten in Pee
por: Silvester, J A, et al.
Publicado: (2015)

Clinical Significance of Loss of ARID1A Expression in Colorectal and Small Intestinal Carcinoma
por: Putra, Juan, et al.
Publicado: (2015)

Muscle at Risk: The Multiple Impacts of Ammonia on Sarcopenia and Frailty in Cirrhosis
por: Chen, Hui-Wei, et al.
Publicado: (2016)

Butyrate and Mucosal Inflammation: New Scientific Evidence Supports Clinical Observation
por: Cushing, Kelly, et al.
Publicado: (2015)

Pharmacology of Rasagiline, a New MAO-B Inhibitor Drug for the Treatment of Parkinson’s Disease with Neuroprotective Potential
por: Finberg, John P.M.
Publicado: (2010)

Impact of Heparanase and the Tumor Microenvironment on Cancer Metastasis and Angiogenesis: Basic Aspects and Clinical Applications
por: Vlodavsky, Israel, et al.
Publicado: (2011)

Coping Flexibility, GI Symptoms, and Functional GI Disorders: How Translational Behavioral Medicine Research Can Inform GI Practice
por: Radziwon, Christopher, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_mhbfuvmdr5mapbmenafn9s72fu