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The Makorin lep-2 and the lncRNA lep-5 regulate lin-28 to schedule sexual maturation of the C. elegans nervous system
Sexual maturation must occur on a controlled developmental schedule. In mammals, Makorin3 (MKRN3) and the miRNA regulators LIN28A/B are key regulators of this process, but how they act is unclear. In C. elegans, sexual maturation of the nervous system includes the functional remodeling of postmitoti...
Autores principales: | Lawson, Hannah, Vuong, Edward, Miller, Renee M, Kiontke, Karin, Fitch, David HA, Portman, Douglas S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606027/ https://www.ncbi.nlm.nih.gov/pubmed/31264582 http://dx.doi.org/10.7554/eLife.43660 |
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