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IL-6-PAD4 axis in the earliest phase of arthritis in knock-in gp130F759 mice, a model for rheumatoid arthritis

OBJECTIVE: Animal models for human diseases are especially valuable for clarifying molecular mechanisms before or around the onset. As a model for rheumatoid arthritis (RA), we utilise knock-in mice gp130F759. They have a Y759F mutation in gp130, a common receptor subunit for interleukin 6 (IL-6) fa...

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Detalles Bibliográficos
Autores principales:	Yahagi, Ayano, Saika, Taro, Hirano, Hiroyasu, Takai-Imamura, Miwa, Tsuji, Fumio, Aono, Hiroyuki, Iseki, Masanori, Morita, Yoshitaka, Igarashi, Hideya, Saeki, Yukihiko, Ishihara, Katsuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Animal Models
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606081/ https://www.ncbi.nlm.nih.gov/pubmed/31321075 http://dx.doi.org/10.1136/rmdopen-2018-000853

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