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Oral Administration of Caffeine Exacerbates Cisplatin-Induced Hearing Loss

Adenosine A(1) receptors (A(1)AR) are well characterized for their role in cytoprotection. Previous studies have demonstrated the presence of these receptors in the cochlea where their activation were shown to suppress cisplatin-induced inflammatory response and the resulting ototoxicity. Inhibition...

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Detalles Bibliográficos
Autores principales: Sheth, Sandeep, Sheehan, Kelly, Dhukhwa, Asmita, Al Aameri, Raheem F. H., Mamillapalli, Chaitanya, Mukherjea, Debashree, Rybak, Leonard P., Ramkumar, Vickram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606569/
https://www.ncbi.nlm.nih.gov/pubmed/31267026
http://dx.doi.org/10.1038/s41598-019-45964-9