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Oral Administration of Caffeine Exacerbates Cisplatin-Induced Hearing Loss
Adenosine A(1) receptors (A(1)AR) are well characterized for their role in cytoprotection. Previous studies have demonstrated the presence of these receptors in the cochlea where their activation were shown to suppress cisplatin-induced inflammatory response and the resulting ototoxicity. Inhibition...
Autores principales: | Sheth, Sandeep, Sheehan, Kelly, Dhukhwa, Asmita, Al Aameri, Raheem F. H., Mamillapalli, Chaitanya, Mukherjea, Debashree, Rybak, Leonard P., Ramkumar, Vickram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606569/ https://www.ncbi.nlm.nih.gov/pubmed/31267026 http://dx.doi.org/10.1038/s41598-019-45964-9 |
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