Liposomal formulation of Galbanic acid improved therapeutic efficacy of pegylated liposomal Doxorubicin in mouse colon carcinoma

Galbanic acid (Gba), a sesquiterpene coumarin, with strong antiangiogenic activity could serve as an excellent anti-cancer agent. However, Gba is a poor water-solube which hampered its clinical application. In this study, a pegylated liposomal Gba (PLGba) with HSPC/Cholesterol/mPEG(2000)-DSPE (56.2,...

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Detalles Bibliográficos
Autores principales: Nik, Maryam Ebrahimi, Malaekeh-Nikouei, Bizhan, Amin, Mohamadreza, Hatamipour, Mahdi, Teymouri, Manouchehr, Sadeghnia, Hamid Reza, Iranshahi, Mehrdad, Jaafari, Mahmoud Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606580/
https://www.ncbi.nlm.nih.gov/pubmed/31267009
http://dx.doi.org/10.1038/s41598-019-45974-7

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